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Wednesday, December 26, 2007

Math model of asymmetric distribution of cell membrane proteins 

Roland Wedlich-Söldner
To establish an asymmetric distribution of membrane proteins, diffusion has to be countered for a long enough time to allow the molecules to accumulate and fulfill their functions. This is possible through active and directed transport whose net effects need to outdo diffusion till the necessary concentration of molecules is reached.

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Apart from diffusion which prevents locally elevated concentrations of molecules there are only two other cellular mechanisms that influence the distribution of membrane proteins. The already mentioned active transport processes rely on structures of the cytoskeleton to move molecules or whole organelles in specific directions. The process of endocytosis, on the other hand, allows cells to absorb membrane molecules by forming vesicles out of small portions of the cell membrane.

Topics: Cell | Biology


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